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轉錄激活蛋白2α/TFAP2α/AP-2α抗體(ti)
產(chan) 品名稱 | 英文名稱 | 貨號 |
轉錄激活蛋白2α/TFAP2α/AP-2α抗體(ti) | AP2 alpha | GOY-01K0130 |
商品屬性:
英文名稱: AP2 alpha
中文名:轉錄激活蛋白2α/TFAP2α/AP-2α抗體(ti)
別 名;Activating
enhancer binding protein 2 alpha; Activating enhancer-binding protein 2-alpha;
Activator protein 2; AP 2; AP 2 transcription factor; AP 2alpha; AP-2; AP-2
transcription factor; AP2; AP2 Transcription Factor; AP2-alpha; AP2A_HUMAN;
AP2TF; BOFS; Clathrin Adaptor Protein Complex; FLJ51761; TFAP 2; TFAP 2A;
TFAP2; TFAP2A; Transcription factor AP 2 alpha (activating enhancer binding
protein 2 alpha); Transcription factor AP 2 alpha; Transcription factor
AP-2-alpha; Transcription factor AP2 alpha.
研究領域;腫瘤 免疫學 信號轉導 細胞凋亡 轉錄調節因子
抗體(ti) 來源;Rabbit
克隆類型;Polyclonal
交叉反應;Mouse, (predicted: Human, Rat, Chicken,
Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chan) 品應用;WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;48kDa
細胞定位;細胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human AP2 alpha
亞(ya) 型;IgG
純化方法;affinity
purified by Protein A
緩 衝(chong) 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chan) 品介紹:
The protein encoded by this gene is a transcription
factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein
functions as either a homodimer or as a heterodimer with similar family
members. This protein activates the transcription of some genes while
inhibiting the transcription of others. Defects in this gene are a cause of
branchiooculofacial syndrome (BOFS). Three transcript variants encoding
different isoforms have been found for this gene. Function: Sequence-specific DNA-binding protein that
interacts with inducible viral and cellular enhancer elements to regulate
transcription of selected genes. AP-2 factors bind to the consensus sequence
5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important
biological functions including proper eye, face, body wall, limb and neural
tube development. They also suppress a number of genes including MCAM/MUC18,
C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early
morphogenesis of the lens vesicle. Together with the CITED2 coactivator,
stimulates the PITX2 P1 promoter transcription activation. Associates with
chromatin to the PITX2 P1 promoter region. |


多克隆抗體(ti) 製備:
我公司合成抗原,保證陽性血清和抗體(ti) ELISA效價(jia) 達到1:32000,由蛋白抗原製備的多抗,保證WB檢測結果是陽性。技術服務實行分步報價(jia) ,按節點收費,為(wei) 客戶節約成本。
鼠單克隆抗體(ti) 製備:
客戶可根據項目實際需求情況靈活選擇進行,我公司將為(wei) 您的項目提供專(zhuan) 業(ye) 的建議。在製備過程中,與(yu) 客戶互動驗證,確保最終製備的抗體(ti) ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體(ti) 最終應用驗證需求。技術服務實行分步報價(jia) ,按節點收費,為(wei) 客戶節約成本。

重組抗體(ti) 表達服務:
重組抗體(ti) 技術使製備人源化抗體(ti) 和人源抗體(ti) 成為(wei) 可能,而這是其他常規的多克隆或單克隆抗體(ti) 製備方法無法做到的。我公司已搭建好的抗體(ti) 測序、重組抗體(ti) 表達等先進平台,能為(wei) 客戶提供各種類型的重組抗體(ti) 表達服務,包含鼠源單克隆抗體(ti) 構建及表達、更換恒定區亞(ya) 型的嵌合抗體(ti) 表達,抗體(ti) 人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為(wei) 客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yang) 、抗體(ti) 修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體(ti) 定製服務:
已注冊(ce) 商標,主要用於(yu) 抗體(ti) 藥物發現和開發,是我公司針對有特定應用要求和各種模型測試的客戶量身定製的專(zhuan) 業(ye) 服務,主要麵向工業(ye) 客戶。
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