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5-羥色胺受體(ti) 1E抗體(ti)
產(chan) 品名稱 | 英文名稱 | 貨號 |
5-羥色胺受體(ti) 1E抗體(ti) | 5HT1E Receptor | GOY-01K2319 |
商品屬性:
英文名稱: 5HT1E Receptor
中文名:5-羥色胺受體(ti) 1E抗體(ti)
別 名;SR-1E; 5
hydroxytryptamine (serotonin) receptor 1E; 5 hydroxytryptamine (serotonin)
receptor 1E G protein coupled; 5 hydroxytryptamine 1E receptor; 5-HT-1E;
5-hydroxytryptamine receptor 1E; HTR1E; S31; Serotonin receptor 1E;
5HT1E_HUMAN.
研究領域;神經生物學 信號轉導 G蛋白偶聯受體(ti) 新陳代謝 G蛋白信號
抗體(ti) 來源;Rabbit
克隆類型;Polyclonal
交叉反應;(predicted:
Human, Pig, Cow, Guinea Pig, )
產(chan) 品應用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修複)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;42kDa
細胞定位;細胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E: 1-120/365
<Extracellular>
亞(ya) 型;IgG
純化方法;affinity
purified by Protein A
緩 衝(chong) 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chan) 品介紹:
The members of the G-protein-coupled receptor
family are distinguished by their slow transmitting response to ligand
binding. These seven transmembrane proteins include the adrenergic, serotonin
and dopamine receptors. The effect of the signaling molecule can be
excitatory or inhibitory depending on the type of receptor to which it binds.
b-adrenergic bound to adrenaline activates adenylyl cyclase, while
a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like
the a2-adrenergic receptor, serotonin receptor functions are also mediated by
G proteins that inhibit the activity of adenylyl cyclase. The serotonin
receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within
the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Function: This is one of the several different receptors for
5-HT, a biogenic hormone that functions as a neurotransmitter, a hormone, and
a mitogen. The activity of this receptor is mediated by G proteins that
inhibit adenylate cyclase activity. The 5-HT1E receptor is expressed in human
cortex, caudate, putamen, and amygdala, as well as in dorsal root ganglia and
in coronary artery. ESTs have been isolated from human brain cancer
libraries. |


多克隆抗體(ti) 製備:
我公司合成抗原,保證陽性血清和抗體(ti) ELISA效價(jia) 達到1:32000,由蛋白抗原製備的多抗,保證WB檢測結果是陽性。技術服務實行分步報價(jia) ,按節點收費,為(wei) 客戶節約成本。
鼠單克隆抗體(ti) 製備:
客戶可根據項目實際需求情況靈活選擇進行,我公司將為(wei) 您的項目提供專(zhuan) 業(ye) 的建議。在製備過程中,與(yu) 客戶互動驗證,確保最終製備的抗體(ti) ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體(ti) 最終應用驗證需求。技術服務實行分步報價(jia) ,按節點收費,為(wei) 客戶節約成本。

重組抗體(ti) 表達服務:
重組抗體(ti) 技術使製備人源化抗體(ti) 和人源抗體(ti) 成為(wei) 可能,而這是其他常規的多克隆或單克隆抗體(ti) 製備方法無法做到的。我公司已搭建好的抗體(ti) 測序、重組抗體(ti) 表達等先進平台,能為(wei) 客戶提供各種類型的重組抗體(ti) 表達服務,包含鼠源單克隆抗體(ti) 構建及表達、更換恒定區亞(ya) 型的嵌合抗體(ti) 表達,抗體(ti) 人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為(wei) 客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yang) 、抗體(ti) 修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體(ti) 定製服務:
已注冊(ce) 商標,主要用於(yu) 抗體(ti) 藥物發現和開發,是我公司針對有特定應用要求和各種模型測試的客戶量身定製的專(zhuan) 業(ye) 服務,主要麵向工業(ye) 客戶。
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